Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures
نویسندگان
چکیده
منابع مشابه
Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures.
Most, if not all, human phenotypes exhibit a temporal, dosage-dependent, or age effect. Despite this fact, it is rare that data are collected over time or in sequence in relevant studies of the determinants of these phenotypes. The costs and organizational sophistication necessary to collect repeated measurements or longitudinal data for a given phenotype are clearly impediments to this, but gr...
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Multivariate distance matrix regression (MDMR) analysis is a statistical technique that allows researchers to relate P variables to an additional M factors collected on N individuals, where P ≫ N. The technique can be applied to a number of research settings involving high-dimensional data types such as DNA sequence data, gene expression microarray data, and imaging data. MDMR analysis involves...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2010
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00118.2009